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Article

Proteomic study of macrophages exposed to oxLDL identifies a CAPG polymorphism associated with carotid atherosclerosis.

Atherosclerosis - 1 Nov 2009

Burillo Elena, Recalde Delia, Jarauta Estibaliz, Fiddyment Sarah, Garcia-Otin Angel Luis, Mateo-Gallego Rocio, Cenarro Ana, Civeira Fernando

Abstract excerpt

OBJECTIVE: Macrophages play a key role in the development of atherosclerosis. The objective of this observational study was to characterize the proteome of macrophages to identify proteins implicated in atherosclerosis. METHODS: The proteome of macrophage exposed to oxidized low-density lipoprotein (LDL) was studied in a sample of 12 subjects with autosomal dominant hypercholesterolemia and analyzed according to...

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Topics

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Share to Carotid Artery Diseases
Share to Electrophoresis, Gel, Two-Dimensional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

Share to Lipoproteins, LDL

Share to Mass Spectrometry

Share to Microfilament Proteins

Share to Proteomics

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Source

Identifiers

PMID: 19439302
DOI: 10.1016/j.atherosclerosis.2009.03.054

Genes

CAPG
GSTO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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