Article
Additive effect of LRP8/APOER2 R952Q variant to APOE epsilon2/epsilon3/epsilon4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study.
BMC medical genetics - 13 May 2009
Martinelli Nicola, Olivieri Oliviero, Shen Gong-Qing, Trabetti Elisabetta, Pizzolo Francesca, Busti Fabiana, Friso Simonetta, Bassi Antonella, Li Lin, Hu Ying, Pignatti Pier Franco, Corrocher Roberto, Wang Qing Kenneth, Girelli Domenico
Abstract excerpt
BACKGROUND: The R952Q variant in the low density lipoprotein receptor-related protein 8 (LRP8)/apolipoprotein E receptor 2 (ApoER2) gene has been recently associated with familial and premature myocardial infarction (MI) by means of genome-wide linkage scan/association studies. We were interested in the possible interaction of the R952Q variant with another established cardiovascular genetic risk factor belonging...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.