Masking of diabetic phenotype on a low-energy diet despite persistence of impaired insulin response.

doi:10.1016/0026-0495(91)90121-c

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Article

Masking of diabetic phenotype on a low-energy diet despite persistence of impaired insulin response.

Metabolism: clinical and experimental - 1 Oct 1991

Levy J C, Ward G M, Naylor B A, Williamson D H, Turner R C

Abstract excerpt

Type 2 diabetes has been postulated to be a "thrifty genotype" that aids fuel conservation; to investigate this hypothesis, type 2 diabetic and nondiabetic subjects, normal weight and obese, were studied after both 6 days on a 700-calorie diet and 6 days on a 2,800-calorie diet. On 2,800 calories per day, the median basal plasma glucose was raised in diabetics compared with nondiabetic subjects (median, 5.5 and...

Topics

Adult
Aged
Blood Glucose
Diabetes Mellitus
Diet
Eating
Energy Metabolism
Female
Glucose
Glucose Tolerance Test
Humans
Injections, Intravenous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin

Insulin Secretion

Ketone Bodies

Male

Middle Aged

Osmolar Concentration

Source

Open in PubMed

Identifiers

PMID: 1943725
DOI: 10.1016/0026-0495(91)90121-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1943725-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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