Article
The -271 G>A polymorphism of kinase insert domain-containing receptor gene regulates its transcription level in patients with non-small cell lung cancer.
BMC cancer - 12 May 2009
An She-Juan, Chen Zhi-Hong, Lin Qiu-Xiong, Su Jian, Chen Hua-Jun, Lin Jia-Ying, Wu Yi-Long
Abstract excerpt
BACKGROUND: Kinase insert domain-containing receptor (KDR) plays a critical role in the metastasis of cancer and is used as a molecular target in cancer therapy. We investigated the characteristics of the -271 G>A polymorphism of the KDR gene to gain information that may benefit the development of individualized therapies for patients with non-small cell lung cancer (NSCLC). METHODS: The -271 G>A polymorphism of...
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