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Article

Role of the K2 capsule in Escherichia coli urinary tract infection and serum resistance.

The Journal of infectious diseases - 1 Jun 2009

Buckles Eric L, Wang Xiaolin, Lane M Chelsea, Lockatell C Virginia, Johnson David E, Rasko David A, Mobley Harry L T, Donnenberg Michael S

Abstract excerpt

BACKGROUND: Capsule expression may be important during ascending Escherichia coli urinary tract infections (UTIs). METHODS: An isogenic ksl(k2)ABCDE mutant of extraintestinal pathogenic E. coli (ExPEC) strain CFT073 that could not synthesize the K2 capsule was compared with wild-type CFT073, to determine virulence in a murine model of ascending UTI and in vitro killing assays. RESULTS: No significant differences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19432551
DOI: 10.1086/598524
PMCID: PMC3872369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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