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Article

The induction of autophagy by γ‐radiation contributes to the radioresistance of glioma stem cells

27 Feb 2009

Abstract excerpt

Malignant gliomas are characterized by a short median survival which is largely impacted by the resistance of these tumors tochemo- and radiotherapy. Recent studies suggest that a small subpopulation of cancer stem cells, which are highly resistant to gamma-radiation, has the capacity to repopulate the tumors and contribute to their malignant progression. gamma-radiation activates the process of autophagy and...

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PMID: 19431142
DOI: 10.1002/ijc.24402

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