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Article

Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments

17 Feb 2012

Abstract excerpt

Glioblastoma (GB) has a poor prognosis, despite current multimodality treatment. Beside surgical resection, adjuvant ionizing radiation (IR) combined with Temozolomide (TMZ) drug administration is the standard therapy for GB. This currently combined radio-chemotherapy treatment resulted in glial tumor cell death induction, whose main molecular death pathways are still not completely deciphered. In this study, the...

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PMID: 22345070
DOI: 10.1002/jcb.24102

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