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Article

The role of autophagy in sensitizing malignant glioma cells to radiation therapy

5 Apr 2009

Abstract excerpt

Malignant gliomas represent the majority of primary brain tumors. The current standard treatments for malignant gliomas include surgical resection, radiation therapy, and chemotherapy. Radiotherapy, a standard adjuvant therapy, confers some survival advantages, but resistance of the glioma cells to the efficacy of radiation limits the success of the treatment. The mechanisms underlying glioma cell radioresistance...

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PMID: 19430698
DOI: 10.1093/abbs/gmp028

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