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Article

Glioblastoma stem cells resistant to temozolomide-induced autophagy.

5 Jun 2009

Abstract excerpt

BACKGROUND: Recent studies have demonstrated the existence of a small fraction of cells with features of primitive neural progenitor cells and tumor-initiating function in brain tumors. These cells might represent primary therapeutic target for complete eradication of the tumors. This study aimed to determine the resistant phenotype of glioblastoma stem cells (GSCs) to temozolomide (TMZ) and to explore the...

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PMID: 19567133
DOI: 10.3760/cma.j.issn.0366-6999.2009.11.004

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