Article
Historical resistance profile helps to predict salvage failure.
Antiviral therapy - 1 Jan 2009
Zaccarelli Mauro, Lorenzini Patrizia, Ceccherini-Silberstein Francesca, Tozzi Valerio, Forbici Federica, Gori Caterina, Trotta Maria P, Boumis Evangelo, Narciso Pasquale, Perno Carlo F, Antinori Andrea
Abstract excerpt
BACKGROUND: This study compared the predictive value for treatment failure of extended resistance detected in the current genotype resistance test (GRT) versus those from GRT history in patients with multiple combination antiretroviral therapy (cART) failures. METHODS: Patients who underwent three GRT between 1999 and 2007 were included. Extended resistance at genotypic sensitivity score (GSS) using the Rega 7.1...
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