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Article

New paradigms in gastrointestinal stromal tumour management.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 May 2009

Blay J-Y

Abstract excerpt

BACKGROUND: Targeted agents have improved the prognosis for patients with advanced gastrointestinal stromal tumours (GISTs). Many patients exhibit intolerance or resistance to first-line therapy with imatinib mesylate. Sunitinib malate is approved multinationally for the treatment of advanced imatinib-refractory GIST. DESIGN: This article reviews responses to imatinib and sunitinib reported in clinical trials in...

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Source

Identifiers

PMID: 19430004
DOI: 10.1093/annonc/mdp075

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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