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Article

An ab Initio structural model of a nucleoside permease predicts functionally important residues.

The Journal of biological chemistry - 10 Jul 2009

Valdés Raquel, Arastu-Kapur Shirin, Landfear Scott M, Shinde Ujwal

Abstract excerpt

Permeases belonging to the equilibrative nucleoside transporter family promote uptake of nucleosides and/or nucleobases into a wide range of eukaryotes and mediate the uptake of a variety of drugs used in the treatment of cancer, heart disease, AIDS, and parasitic infections. No experimental three-dimensional structure exists for any of these permeases, and they are not present in prokaryotes, the source of many...

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Identifiers

PMID: 19429678
DOI: 10.1074/jbc.M109.017947
PMCID: PMC2707223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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