Article
Characterization of antigenic epitopes of the ORF2 protein from hepatitis E virus genotype 4.
Virus research - 1 Jun 2009
Zhang Hongmei, Dai Xing, Shan Xiangnian, Meng Jihong
Abstract excerpt
This study was aimed to characterize antigenic epitopes of a newly identified hepatitis E virus (HEV) Chinese strain of genotype 4. Recombinant capsid protein p166Chn (amino acids 464-629) and six murine monoclonal antibodies (mAbs) against the protein were prepared. The mAbs were evaluated for their ability to neutralize a genotype 4 HEV strain by an in vitro PCR-based HEV neutralization assay. The antigenic...
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