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Design and evaluation of a recombinant multi-epitope-based ELISA for the serological surveillance of HEV infection in northern China.

Archives of virology - 1 Sept 2011

Shenyang Gao, Dandan Li, Chen Fan, Shuliang Wu, Tiezhong Zhou

Abstract excerpt

In this study, seven recombinant epitope peptides from within the ORF2 protein of the local genotype 4 swine hepatitis E virus (HEV) DQ strain were designed and analyzed. Then, a new multi-epitope-based ELISA was established. In comparison with a commercial kit, this test exhibited good specificity and sensitivity for anti-HEV genotype 4. Subsequently, this test was applied for analyzing serum samples from either...

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PMID: 21544544
DOI: 10.1007/s00705-011-1007-y

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