Article
GSTM1 copy number and lung cancer risk.
Mutation research - 12 May 2009
Crosbie Philip A J, Barber Philip V, Harrison Kathryn L, Gibbs Alan R, Agius Raymond M, Margison Geoffrey P, Povey Andrew C
Abstract excerpt
The GSTM1 null genotype is associated with a small increased lung cancer risk when compared to controls with at least one copy of the GSTM1 gene. As two copies of the GSTM1 gene might provide more protection than a single copy, we have determined GSTM1 copy number in a lung cancer case-control study. Cases with incident lung cancer were identified through a Bronchoscopy Unit and two separate hospital based...
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