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Article

Copy number variants of GSTM1 and GSTT1 in relation to lung cancer risk in a prospective cohort study.

Annals of epidemiology - 1 Aug 2009

Lam Tram Kim, Ruczinski Ingo, Helzlsouer Kathy, Shugart Yin Yao, Li Kelly E, Clipp Sandra, Strickland Paul T, Alberg Anthony J

Abstract excerpt

PURPOSE: Previous studies did not discriminate wild-type from hemizygous genotypes of GSTM1 and GSTT1. In this study, we investigated wild-type, hemizygous deletion, and homozygous deletion genotypes of GSTM1 and GSTT1 and lung cancer risk. METHODS: We conducted a nested case-control study of 143 primary incident lung cancer cases matched to 447 cancer-free controls. Genotyping was carried out using a real-time...

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Source

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Identifiers

PMID: 19394866
DOI: 10.1016/j.annepidem.2009.03.003
PMCID: PMC2720160

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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