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Article

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications.

Haematologica - 1 Jun 2017

Wu Shang-Ju, Lin Chien-Ting, Agathangelidis Andreas, Lin Liang-In, Kuo Yuan-Yeh, Tien Hwei-Fang, Ghia Paolo

Abstract excerpt

Differences in chronic lymphocytic leukemia between the Asian and the Western population are widely known. To further clarify these ethnic differences, we profiled the molecular genetics in a cohort of 83 newly diagnosed patients from Taiwan. In detail, we assessed: (i) the usage and the mutational status of the clonotypic immunoglobulin heavy-chain variable region (IgHV) genes, (ii) the presence of VH CDR3...

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Share to Asian People
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin Heavy Chain

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

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Identifiers

PMID: 28255015
DOI: 10.3324/haematol.2016.157552
PMCID: PMC5451340

Genes

MYD88
NOTCH1

Provenance

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