Article
Polymorphism C1114G of gene encoding the cardiac regulator of G-protein signaling 2 may be associated with number of episodes of neurally mediated syncope.
Archives of medical research - 1 Apr 2009
Lelonek Malgorzata, Pietrucha Tadeusz, Matyjaszczyk Monika, Goch Jan Henryk
Abstract excerpt
BACKGROUND AND AIMS: The cardiac regulator of G-protein signaling 2 (RGS2) negatively regulates G-protein-coupled receptor signaling. The C1114G polymorphism reduces RGS2 gene expression. This molecular disorder may be one of the important factors influencing progress of neurally mediated syncope. The aim of the study was to evaluate the association between C1114G RGS2 polymorphism and tilting results and number...
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