Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Importance of gene variants and co-factors of folate metabolic pathway in the etiology of idiopathic intellectual disability.

Nutritional neuroscience - 1 Sept 2011

Dutta Samikshan, Shaw Jyoti, Chatterjee Arpita, Sarkar Kanyakumarika, Usha Rajamma, Chatterjee Anindita, Sinha Swagata, Mukhopadhyay Kanchan

Abstract excerpt

Different components of the folate metabolic cycle are crucial for maintaining integrity of DNA. The present study was aimed at exploring the role of some important constituents of the folate cycle in the etiology of idiopathic intellectual disability (IID). Nuclear families with IID probands (n=226) and ethnically matched controls (n=181) were recruited for micronucleus, karyotype, genetic polymorphism (MTR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epistasis, Genetic
Share to Family Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ferredoxin-NADP Reductase

Share to Folic Acid

Share to Intellectual Disability

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Tetrahydrofolate Dehydrogenase

Share to Vitamin B 6

Source

Identifiers

PMID: 22005284
DOI: 10.1179/1476830511Y.0000000016

Genes

DHFR
MTR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Importance of gene variants and co-factors of folate metabolic pathway in the etiology of idiopathic intellectual disability.PMID 22005284Read ↗

Mechanisms of genome instability from cellular folate stressSemantic proximity Read ↗

Genetic polymorphisms in folate and homocysteine metabolism as risk factors for DNA damageSemantic proximity Read ↗

Components of the folate metabolic pathway and ADHD core traits: an exploration in eastern Indian probands.Semantic proximity Read ↗

Polymorphisms in 1-carbon metabolism, epigenetics and folate-related pathologies.Semantic proximity Read ↗

Perspectives on folate with special reference to epigenetics and neural tube defectsSemantic proximity Read ↗

Analysis of association between components of the folate metabolic pathway and autism spectrum disorder in eastern Indian subjects.Semantic proximity Read ↗

Genetic defects in folate and cobalamin pathways affecting the brain.Semantic proximity Read ↗

Nuclear Folate MetabolismSemantic proximity Read ↗

Methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.Semantic proximity Read ↗

Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder.Semantic proximity Read ↗

Unveiling the Therapeutic Potential of Folate-Dependent One-Carbon Metabolism in Cancer and NeurodegenerationSemantic proximity Read ↗

Folate: Metabolism, genes, polymorphisms and the associated diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.