Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive mutation scanning of LMNA in 268 patients with lone atrial fibrillation.

The American journal of cardiology - 15 May 2009

Brauch Katharine M, Chen Lin Y, Olson Timothy M

Abstract excerpt

Atrial fibrillation (AF) is a heritable, genetically heterogeneous disorder. To identify gene defects that cause or confer susceptibility to AF, a cohort of 268 unrelated patients with idiopathic forms of familial and sporadic AF was recruited. LMNA, encoding the nuclear membrane proteins, lamin A/C, was selected as a candidate gene for lone AF based on its established association with a syndrome of dilated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lamin Type A
Share to Mutation
Share to Atrial Fibrillation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiomyopathy, Dilated

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Polymerase Chain Reaction

Share to Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 19427440
DOI: 10.1016/j.amjcard.2009.01.354
PMCID: PMC2697665

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive mutation scanning of LMNA in 268 patients with lone atrial fibrillation.PMID 19427440Read ↗

Variants of the lamin A/C (LMNA) gene in non-valvular atrial fibrillation patients: a possible pathogenic role of the Thr528Met mutation.Semantic proximity Read ↗

Genetic aspects of lone atrial fibrillation: what do we know?Semantic proximity Read ↗

Common variants in KCNN3 are associated with lone atrial fibrillation.Semantic proximity Read ↗

Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers.Semantic proximity Read ↗

A novel mutation of the LMNA gene in a family with dilated cardiomyopathy, conduction system disease, and sudden cardiac death of young females.Semantic proximity Read ↗

Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation.Semantic proximity Read ↗

A novel lamin A/C mutation in a family with dilated cardiomyopathy, prominent conduction system disease, and need for permanent pacemaker implantation.Semantic proximity Read ↗

Expanding the phenotype of LMNA mutations in dilated cardiomyopathy and functional consequences of these mutations.Semantic proximity Read ↗

Identification of novel mutations in LMNA associated with familial forms of dilated cardiomyopathy.Semantic proximity Read ↗

Identification of mutational hot spots in LMNA encoding lamin A/C in patients with familial dilated cardiomyopathy.Semantic proximity Read ↗

High yield of LMNA mutations in patients with dilated cardiomyopathy and/or conduction disease referred to cardiogenetics outpatient clinics.Semantic proximity Read ↗

Mutation analysis of the lamin A/C gene (LMNA) among patients with different cardiomuscular phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.