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Article

Variants of the lamin A/C (LMNA) gene in non-valvular atrial fibrillation patients: a possible pathogenic role of the Thr528Met mutation.

Molecular diagnosis & therapy - 1 Apr 2012

Saj Michal, Dabrowski Rafal, Labib Sarah, Jankowska Agnieszka, Szperl Malgorzata, Broda Grazyna, Szwed Hanna, Tesson Frederique, Bilinska Zofia T, Ploski Rafal

Abstract excerpt

BACKGROUND AND OBJECTIVE: Lamin A/C (LMNA) gene mutations cause dilated cardiomyopathy, often accompanied by conduction disturbances. Our aim was to search for LMNA mutations in individuals with atrial fibrillation. METHODS: A cohort of Polish subjects (N = 103) with non-valvular atrial fibrillation with a high (48.5%) prevalence of conduction system disturbances was screened for LMNA variants by direct DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22413764
DOI: 10.1007/BF03256434

Genes

LMNA

Variants

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Related research

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Variants of the lamin A/C (LMNA) gene in non-valvular atrial fibrillation patients: a possible pathogenic role of the Thr528Met mutation.PMID 22413764Read ↗

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