Article
Host genetics maps to behaviour and brain structure in developmental mice.
Behavioral and brain functions : BBF - 2 Jan 2025
Asbury Sarah, Lai Jonathan K Y, Rilett Kelly C, Haqqee Zeeshan, Darwin Benjamin C, Ellegood Jacob, Lerch Jason P, Foster Jane A
Abstract excerpt
Gene-environment interactions in the postnatal period have a long-term impact on neurodevelopment. To effectively assess neurodevelopment in the mouse, we developed a behavioural pipeline that incorporates several validated behavioural tests to measure translationally relevant milestones of behaviour in mice. The behavioral phenotype of 1060 wild type and genetically-modified mice was examined followed by...
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