Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction in the Mouse

22 Nov 2013

Abstract excerpt

The Y chromosome is thought to be important for male reproduction. We have previously shown that, with the use of assisted reproduction, live offspring can be obtained from mice lacking the entire Y chromosome long arm. Here, we demonstrate that live mouse progeny can also be generated by using germ cells from males with the Y chromosome contribution limited to only two genes, the testis determinant factor Sry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sexual Differentiation and Disorders
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24263135
DOI: 10.1126/science.1242544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction in the MousePMID 24263135Read ↗

Two genes substitute for the mouse Y chromosome for spermatogenesis and reproductionSemantic proximity Read ↗

Y chromosome functions in mammalian spermatogenesis.Semantic proximity Read ↗

A New Deletion of the Mouse Y Chromosome Long Arm Associated With the Loss ofSstyExpression, Abnormal Sperm Development and SterilitySemantic proximity Read ↗

Systematic identification of Y-chromosome gene functions in mouse spermatogenesisSemantic proximity Read ↗

Systematic identification of Y-chromosome gene functions in mouse spermatogenesisSemantic proximity Read ↗

Y Chromosome Genes May Play Roles in Directed Differentiation of Human Embryonic Stem Cells.Semantic proximity Read ↗

TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse SpermatogenesisSemantic proximity Read ↗

Spermatid development in XO male mice with varying Y chromosome short-arm gene content: evidence for a Y gene controlling the initiation of sperm morphogenesisSemantic proximity Read ↗

Roles of the Y chromosome genes in human cancersSemantic proximity Read ↗

Germ cell-intrinsic effects of sex chromosomes on early oocyte differentiation in miceSemantic proximity Read ↗

[Evolution and mutation of human Y chromosome and their relationship with male infertility].Semantic proximity Read ↗

Human SRY Expression at the Sex-determining Period is Insufficient to Drive Testis Development in Mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.