Article
TANDEM: integrating automated allele binning into genetics and genomics workflows.
Bioinformatics (Oxford, England) - 1 Aug 2009
Matschiner Michael, Salzburger Walter
Abstract excerpt
SUMMARY: Computer programs for the statistical analysis of microsatellite data use allele length variation to infer, e.g. population genetic parameters, to detect quantitative trait loci or selective sweeps. However, observed allele lengths are usually inaccurate and may deviate from the expected periodicity of repeats. The common practice of rounding to the nearest whole number frequently results in miscalls and...
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