Article
Differential requirement for nucleostemin in embryonic stem cell and neural stem cell viability.
Stem cells (Dayton, Ohio) - 1 May 2009
Nomura Jun, Maruyama Masayoshi, Katano Miyuki, Kato Hidemasa, Zhang Jiaxing, Masui Shinji, Mizuno Yosuke, Okazaki Yasushi, Nishimoto Masazumi, Okuda Akihiko
Abstract excerpt
Stem cells have the remarkable ability to self-renew and to generate multiple cell types. Nucleostemin is one of proteins that are enriched in many types of stem cells. Targeted deletion of nucleostemin in the mouse results in developmental arrest at the implantation stage, indicating that nucleo...
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