Article
[Inherited cardiac diseases caused by Nav1.5 sodium channel mutations].
Ugeskrift for laeger - 6 Apr 2009
Tfelt-Hansen Jacob, Olesen Søren-Peter, Svendsen Jesper Hastrup, Jespersen Thomas
Abstract excerpt
Contraction of the heart is achieved through a delicately regulated conduction of electrical impulses. A pivotal element in the impulse propagation is the depolarising sodium current responsible for the initial depolarisation of the cardiomyocytes. Recent research has shown that mutations in the...
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