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Article

Genetic and environmental pathways to complex diseases.

BMC systems biology - 5 May 2009

Gohlke Julia M, Thomas Reuben, Zhang Yonqing, Rosenstein Michael C, Davis Allan P, Murphy Cynthia, Becker Kevin G, Mattingly Carolyn J, Portier Christopher J

Abstract excerpt

BACKGROUND: Pathogenesis of complex diseases involves the integration of genetic and environmental factors over time, making it particularly difficult to tease apart relationships between phenotype, genotype, and environmental factors using traditional experimental approaches. RESULTS: Using gene-centered databases, we have developed a network of complex diseases and environmental factors through the...

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Identifiers

PMID: 19416532
DOI: 10.1186/1752-0509-3-46
PMCID: PMC2680807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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