Article
Comparative whole-genome analysis of Streptococcus mutans isolates within and among individuals of different caries status.
Oral microbiology and immunology - 1 Jun 2009
Zhang L, Foxman B, Drake D R, Srinivasan U, Henderson J, Olson B, Marrs C F, Warren J J, Marazita M L
Abstract excerpt
INTRODUCTION: Genotypic analyses of Streptococcus mutans using fingerprinting methods depend on a few genetic loci being different but do not reveal the underlying genome-wide differences between strains. METHODS: We used comparative genomic hybridization (CGH) with 70-mer oligonucleotide microarrays containing open reading frames (ORFs) from S. mutans strain UA159 to examine the genetic diversity of 44 isolates...
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