Article
A possible mechanism of low molecular weight protein tyrosine phosphatase (LMW-PTP) activity modulation by glutathione action during human osteoblast differentiation.
Archives of oral biology - 1 Jul 2009
de Souza Malaspina Tatiana Salles, Zambuzzi Willian Fernando, dos Santos Célio Xavier, Campanelli Ana Paula, Laurindo Francisco Rafael Martins, Sogayar Mari Cleide, Granjeiro José Mauro
Abstract excerpt
OBJECTIVE: Low molecular weight protein tyrosine phosphatases (LMW-PTPs) are a family of enzymes strongly involved in the regulation of cell growth and differentiation. Since there is no information concerning the relationship between osteoblastic differentiation and LMW-PTP expression/activity, we investigated its involvement during human osteoblast-like cells (hFOB 1.19) differentiation. It is known that...
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