Article
Transcriptional activation of the tyrosine phosphatase gene, OST-PTP, during osteoblast differentiation.
Journal of cellular biochemistry - 1 Jan 2002
Wheeler Marie A, Townsend Melanie K, Yunker Laurie A, Mauro Laura J
Abstract excerpt
Protein tyrosine phosphatases (PTPs) are critical regulators of cellular phosphorylation functioning in processes such as cell growth, differentiation, and adhesion. Osteotesticular PTP (OST) is the only characterized member of this superfamily whose expression is regulated in osteoblasts and critical for their in vitro differentiation. Such evidence would suggest that this molecule is a key modulator of...
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