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Article

Effects of paraoxonase 1 on the cytodifferentiation and mineralization of periodontal ligament cells.

Journal of periodontal research - 1 Apr 2018

Masumoto R, Kitagaki J, Matsumoto M, Miyauchi S, Fujihara C, Yamashita M, Yamada S, Kitamura M, Murakami S

Abstract excerpt

BACKGROUND AND OBJECTIVE: Single nucleotide polymorphisms (SNPs) of paraoxonase 1 (PON1) are known to be associated with the pathogenesis of osteoporosis and periodontitis. However, the effects of PON1 on the osteoblastic differentiation of periodontal ligament (PDL) cells are unclear. In this study, we examined the effects of PON1 on the osteoblastic differentiation of PDL cells, and analysed the role of PON1...

Read the complete abstract on PubMed

Topics

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Share to Aggressive Periodontitis
Share to Alkaline Phosphatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aryldialkylphosphatase

Share to Bone Resorption

Share to Calcification, Physiologic

Share to Osteoblasts

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Source

Identifiers

PMID: 29063603
DOI: 10.1111/jre.12507

Genes

PON1
HPDL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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