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Article

Total serum tryptase: a predictive marker for KIT mutation in acute myeloid leukemia.

Leukemia research - 1 Sept 2009

Cairoli Roberto, Ripamonti Carla Barbara, Beghini Alessandro, Granata Simonetta, Grillo Giovanni, Brioschi Matteo, Nadali Gianpaolo, Viola Assunta, Cattaneo Chiara, Inropido Liliana, Ravelli Erika, Bertani Giambattista, Pezzetti Laura, Nichelatti Michele, Marocchi Alessandro, Rossi Giuseppe, Pizzolo Giovanni, Ferrara Felicetto, Nosari Anna Maria, Morra Enrica

Abstract excerpt

Human tryptase is a serine protease expressed in mast-cells. We previously observed that AML blast cells, cultured in vitro from a KIT D816Y patient, give rise to adherent cells with mast-cell like phenotype and tryptase was released in the serum-free medium. To correlate total serum tryptase (ts...

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Source

Identifiers

PMID: 19406474
DOI: 10.1016/j.leukres.2009.03.043

Genes

KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19406474-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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