Article
Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.
BMC infectious diseases - 1 May 2009
Wang Yan, Yan Jiangwei, Shi Yuling, Li Ping, Liu Chuanxuan, Ma Qingjun, Yang Ruifu, Wang Xiaoyi, Zhu Lina, Yang Xiao, Cao Cheng
Abstract excerpt
BACKGROUND: The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population....
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