Article
Genetic variation of the human α-2-Heremans-Schmid glycoprotein (AHSG) gene associated with the risk of SARS-CoV infection.
PloS one - 1 Jan 2011
Zhu Xiaohui, Wang Yan, Zhang Hongxing, Liu Xuan, Chen Ting, Yang Ruifu, Shi Yuling, Cao Wuchun, Li Ping, Ma Qingjun, Zhai Yun, He Fuchu, Zhou Gangqiao, Cao Cheng
Abstract excerpt
Genetic background may play an important role in the process of SARS-CoV infection and SARS development. We found several proteins that could interact with the nucleocapsid protein of the SARS coronavirus (SARS-CoV). α-2-Heremans-Schmid Glycoprotein (AHSG), which is required for macrophage deactivation by endogenous cations, is associated with inflammatory regulation. Cytochrome P450 Family 3A (CYP4F3A) is an...
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