Human leukocyte antigen-DQB1*03 alleles are associated with alopecia areata.

doi:10.1111/1523-1747.ep12412584

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Article

Human leukocyte antigen-DQB1*03 alleles are associated with alopecia areata.

The Journal of investigative dermatology - 1 Dec 1994

Welsh E A, Clark H H, Epstein S Z, Reveille J D, Duvic M

Abstract excerpt

Alopecia areata (AA) is characterized by hair loss in patches (patchy AA), over the entire scalp (AT, totalis), or universally (AU). An autoimmune mechanism has been hypothesized, because the inflammatory infiltrate targeted to the hair follicles includes activated T cells. To investigate whether...

Topics

Alleles
Alopecia Areata
Base Sequence
Gene Amplification
Gene Frequency
HLA-DP Antigens
HLA-DQ Antigens
HLA-DR Antigens
Humans
Molecular Sequence Data
Polymerase Chain Reaction

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