Article
Human leukocyte antigen-DQB1*03 alleles are associated with alopecia areata.
The Journal of investigative dermatology - 1 Dec 1994
Welsh E A, Clark H H, Epstein S Z, Reveille J D, Duvic M
Abstract excerpt
Alopecia areata (AA) is characterized by hair loss in patches (patchy AA), over the entire scalp (AT, totalis), or universally (AU). An autoimmune mechanism has been hypothesized, because the inflammatory infiltrate targeted to the hair follicles includes activated T cells. To investigate whether or not genetic polymorphism of the human leukocyte antigen (HLA) region contributes to disease susceptibility, we used...
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