Article
HLA-DRB1 and HLA-DQB1 genes in susceptibility and resistance to cicatricial pemphigoid in French Caucasians.
European journal of dermatology : EJD - 1 Jan 2000
Drouet M, Delpuget-Bertin N, Vaillant L, Chauchaix S, Boulanger M D, Bonnetblanc J M, Bernard P
Abstract excerpt
Cicatricial pemphigoid (CP) is a chronic, autoimmune, subepithelial blistering disease, characterized by the presence of antibasement membrane antibodies (BMZ) against anchoring filaments components. An association between the HLA-DQB1*0301 allele and ocular cicatricial pemphigoid has been previo...
Topics
- Alleles
- France
- Gene Frequency
- Genes, MHC Class II
- Genetic Linkage
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Pemphigoid, Benign Mucous Membrane
- White People
