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Article

Differential pattern of pre-S mutations/deletions and its association with hepatitis B virus genotypes in Eastern India.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2012

Biswas Avik, Panigrahi Rajesh, Banerjee Arup, Pal Manisha, De Binay Krishna, Chakrabarti Sekhar, Chakravarty Runu

Abstract excerpt

The presence of three different HBV genotypes (A, C and D) in Eastern India provided us a unique opportunity to study HBV pre-S mutants in these genotypes and subtypes among the same ethnic population. Furthermore, we also aimed to investigate the association of the HBV pre-S mutation with clinical outcome. Pre-S1-S2 and S gene was amplified and sequenced from 86 HBsAg positive study subjects with varying...

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PMID: 22266243
DOI: 10.1016/j.meegid.2012.01.007

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