Article
[A study in the Guizhou area on pre-S region mutations of hepatitis B virus].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Feb 2007
Wang Mei, Ding Jing-juan, Liu Yue-hui
Abstract excerpt
OBJECTIVE: To study the relationships between hepatitis B virus (HBV ) pre-S region mutations and their genotypes and the stages of liver disease of the patients. METHODS: The entire HBV pre-S1 and pre-S2 genes were amplified by polymerase chain reaction (PCR). The amplified products were digested by NlaIII restriction enzyme. A detecting method for pre-S2 start codon mutation was established according to the...
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