Article
From alpha to beta: identification of amino acids required for the N-acetyllactosamine-specific lectin-like activity of bundlin.
Molecular microbiology - 1 May 2009
Humphries Romney M, Donnenberg Michael S, Strecker Jonathan, Kitova Elena, Klassen John S, Cui Lina, Griener Thomas P, Mulvey George L, Armstrong Glen D
Abstract excerpt
Bundle-forming pili (BFP) promote the adherence of typical enteropathogenic Escherichia coli (EPEC) to human intestinal epithelial cells. BFP are polymers of bundlin and nine bundlin alleles have been identified in EPEC isolated from diverse sources. These alleles are divided into two main groups, alpha and beta, based on their amino acid sequences. Alpha bundlins are also N-acetyllactosamine- (LacNAc) specific...
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