Influence of methionine synthase (A2756G) and methionine synthase reductase (A66G) polymorphisms on plasma homocysteine levels and relation to risk of coronary artery disease.

doi:10.2143/AC.61.1.2005140

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Article

Influence of methionine synthase (A2756G) and methionine synthase reductase (A66G) polymorphisms on plasma homocysteine levels and relation to risk of coronary artery disease.

Acta cardiologica - 1 Feb 2006

Laraqui Abdelilah, Allami Abdellatif, Carrié Alain, Coiffard Anne-Sophie, Benkouka Fatima, Benjouad Abdelaziz, Bendriss Abdenabi, Kadiri Nizar, Bennouar Nawal, Benomar Anwar, Guedira Abdelghafour, Raisonnier Alain, Fellati Seddik, Srairi Jamal-Eddine, Benomar Mohamed

Abstract excerpt

BACKGROUND: Elevated plasma total homocysteine (tHcy) is increasingly being recognized as a risk factor for coronary artery disease (CAD) and other defects. Recent genetic studies have characterized molecular determinants contributing to altered homocysteine metabolism. Our objectives were therefore to confirm the relationship of tHcy with CAD and to examine the importance of genetic influence on tHcy in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16485733
DOI: 10.2143/AC.61.1.2005140

Genes

CAD
MTR
MTRR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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