Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early effects of Sertoli cell‐selective androgen receptor ablation on testicular gene expression

13 Apr 2009

Abstract excerpt

Evidence from several models of hormone depletion and/or replacement and from knockout animals points to a key role of androgens in the control of spermatogenesis. In testes of mice with a Sertoli cell-selective ablation of the androgen receptor (SCARKO), transcriptional profiling, using microarray technology, revealed that, already on postnatal day 10,692 genes are differentially expressed compared with testes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19392831
DOI: 10.1111/j.1365-2605.2009.00964.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early effects of Sertoli cell‐selective androgen receptor ablation on testicular gene expressionPMID 19392831Read ↗

The Effect of a Sertoli Cell-Selective Knockout of the Androgen Receptor on Testicular Gene Expression in Prepubertal MiceSemantic proximity Read ↗

Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activitySemantic proximity Read ↗

Gene expression alterations by conditional knockout of androgen receptor in adult sertoli cells of Utp14b(jsd/jsd) (jsd) mice.Semantic proximity Read ↗

Gene expression alterations by conditional knockout of androgen receptor in adult Sertoli cells of Utp14b jsd/jsd (jsd) mice.Semantic proximity Read ↗

Temporal Role of Sertoli Cell Androgen Receptor Expression in Spermatogenic DevelopmentSemantic proximity Read ↗

Selective Ablation of the Androgen Receptor in Mouse Sertoli Cells Affects Sertoli Cell Maturation, Barrier Formation and Cytoskeletal DevelopmentSemantic proximity Read ↗

Presumptive pre‐sertoli cells express genes involved in cell proliferation and cell signalling during a critical window in early testis differentiationSemantic proximity Read ↗

Sertoli cell androgen receptor DNA binding domain is essential for the completion of spermatogenesis.Semantic proximity Read ↗

Androgens and spermatogenesis: lessons from transgenic mouse modelsSemantic proximity Read ↗

Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells.Semantic proximity Read ↗

Identification of testosterone-/androgen receptor-regulated genes in mouse Sertoli cellsSemantic proximity Read ↗

Cell‐specific ablation in the testis: what have we learned?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.