Article
Molecular basis of weak D in Taiwanese.
Annals of hematology - 1 Oct 2003
Lin I-L, Shih M-C, Hsieh M-H, Liu T-C, Chang S-E, Lin C-L, Chang J-G
Abstract excerpt
Two genes, RHD and RHCE, encode the antigens of the RH blood group system. The weak D phenotype is caused by many different RHD alleles encoding aberrant RhD proteins, resulting in distinct serologic phenotypes and anti-D immunization. We analyzed seven weak D phenotypes excluding D(el), using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and direct sequencing methods to detect the...
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