Article
IL-18 105 A>C polymorphism contributes to renal manifestations in patients with SLE.
Rheumatology international - 1 Dec 2009
Warchoł Teresa, Lianeri Margarita, Wudarski Mariusz, Lacki Jan K, Jagodziński Paweł Piotr
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multisystem autoimmune connective tissue disorder characterized by various aberrations including increased production of IL-18. As IL-18 105 A>C polymorphic variants have been linked to increased production of this cytokine, we investigated the prevalence of IL-18 105 A>C (rs549908) polymorphic variants in SLE patients (n = 111) and controls (n = 152). There were no...
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