Article
A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients.
Lupus - 1 Feb 2008
Lin Y-J, Wan L, Sheu J J-C, Huang C-M, Lin C-W, Lan Y-C, Lai C-H, Hung C-H, Tsai Y, Tsai C-H, Lin T-H, Chen C-P, Tsai F-J
Abstract excerpt
Interleukin-18 (IL-18) is associated with chronic inflammation, autoimmune diseases and various cancers and infectious diseases. An IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma and rheumatoid arthritis. We tested a hypothesis that the IL-18 genetic polymorphism confers systemic lupus erythematosus (SLE) susceptibility. Study participants were Taiwanese SLE patients...
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