Article
From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging.
The Journal of investigative dermatology - 1 Oct 2009
Capell Brian C, Tlougan Brook E, Orlow Seth J
Abstract excerpt
Despite their rarity, diseases of premature aging, or "progeroid" syndromes, have provided important insights into basic mechanisms that may underlie cancer and normal aging. In this review, we highlight these recent developments in Hutchinson-Gilford progeria syndrome (HGPS), Werner syndrome, Bloom syndrome, Cockayne syndrome, trichothiodystrophy, ataxia-telangiectasia, Rothmund-Thomson syndrome, and xeroderma...
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