Article
Mutations in exon 3 of the CTNNB1 gene (beta-catenin gene) in cutaneous adnexal tumors.
The American Journal of dermatopathology - 1 May 2009
Kazakov Dmitry V, Sima Radek, Vanecek Tomas, Kutzner Heinz, Palmedo Gabriele, Kacerovska Denisa, Grossmann Petr, Michal Michal
Abstract excerpt
Previous studies suggested that mutant beta-catenin gene cells in cutaneous adnexal tumors with matrical differentiation contribute to their tumorigenesis. Except for pilomatricoma and pilomatrical carcinoma, only a handful of other cutaneous adnexal tumor types have been studied. DNA was extracted from 86 lesions including 17 proliferating tricholemmal and trichilemmal tumors, 15 trichoblastomas, 7...
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