Article
Allelic status of 1p and 19q in oligodendrogliomas and glioblastomas: multiplex ligation-dependent probe amplification versus loss of heterozygosity.
Cancer genetics and cytogenetics - 15 Apr 2009
Franco-Hernández Carmen, Martínez-Glez Victor, de Campos Jose M, Isla Alberto, Vaquero Jesús, Gutiérrez Manuel, Casartelli Cacilda, Rey Juan A
Abstract excerpt
Identification of the 1p/19q allelic status in gliomas, primarily those with a major oligodendroglial component, has become an excellent molecular complement to tumor histology in order to identify those cases sensitive to chemotherapy. In addition to loss of heterozygosity (LOH), fluorescence in situ hybridization (FISH), or comparative genomic hybridization (CGH), multiplex ligation-dependent probe...
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