Article
Recruitment of the ParG segregation protein to different affinity DNA sites.
Journal of bacteriology - 1 Jun 2009
Zampini Massimiliano, Derome Andrew, Bailey Simon E S, Barillà Daniela, Hayes Finbarr
Abstract excerpt
The segrosome is the nucleoprotein complex that mediates accurate plasmid segregation. In addition to its multifunctional role in segrosome assembly, the ParG protein of multiresistance plasmid TP228 is a transcriptional repressor of the parFG partition genes. ParG is a homodimeric DNA binding protein, with C-terminal regions that interlock into a ribbon-helix-helix fold. Antiparallel beta-strands in this fold...
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