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Article

Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines.

Pharmacogenomics - 1 Apr 2009

Duan Shiwei, Huang R Stephanie, Zhang Wei, Mi Shuangli, Bleibel Wasim K, Kistner Emily O, Cox Nancy J, Dolan M Eileen

Abstract excerpt

AIM: Folate is vital for cell growth and development through its important role in one-carbon metabolism - an essential process in the synthesis of amino acids and nucleic acids. Folate pathway genes have been considered as therapeutic targets of drugs for the treatment of cancer and other diseases. Racial and ethnic disparities of folate metabolism and outcome of antifolate therapies have been reported. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19374514
DOI: 10.2217/pgs.09.8
PMCID: PMC2709842

Genes

DDX52
FPGS
IFIH1
RUVBL2
SETX
SMARCA2
SMARCA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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