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Article

Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study

2 Apr 2019

Abstract excerpt

BACKGROUND: There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome. Alcohol, which can disrupt folate absorption, is also known to affect the epigenome. We investigated the association of dietary folate and alcohol intake on leukocyte DNA methylation levels in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Leukocyte...

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PMID: 30940212
DOI: 10.1186/s13148-019-0637-x

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